MDM4 (MDMX) and its Transcript Variants
نویسندگان
چکیده
منابع مشابه
MDM4 (MDMX) and its Transcript Variants
MDM family proteins are crucial regulators of the oncosuppressor p53. Alterations of their gene status, mainly amplification events, have been frequently observed in human tumors.MDM4 is one of the two members of the MDM family. The human gene is located on chromosome 1 at q32-33 and codes for a protein of 490aa. In analogy to MDM2, besides the full-length mRNA several transcript variants of MD...
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ژورنال
عنوان ژورنال: Current Genomics
سال: 2009
ISSN: 1389-2029
DOI: 10.2174/138920209787581280